Peptide database

5-Amino-1MQ is a small molecule, not a peptide, that blocks the enzyme NNMT in fat cells. Mouse studies show reduced fat mass and improved metabolic markers; there are no human trials of any kind.

AHK-Cu is a copper-bound tripeptide closely related to GHK-Cu that is used mainly for hair growth. It is applied topically to the scalp, often with microneedling, and has cell and small human study evidence for stimulating hair follicle cells.

AOD-9604 is a modified 16 amino acid fragment of the C-terminal end of human growth hormone, built to keep the fat burning signal of HGH without the growth or insulin effects. It lost its only real test: large phase 2 trials in obese adults found no meaningful weight loss, and the program was abandoned.

BPC-157 is a 15 amino acid fragment of a protective protein found in human gastric juice. People use it for tendon, ligament, muscle and gut healing, and it is one of the most widely used research peptides in the recovery space.

Cagrilintide is a long-acting analogue of the hormone amylin that reduces appetite through a different pathway than GLP-1 drugs. Alone it produced about 11 percent weight loss in Phase 2; paired with semaglutide as CagriSema it reached about 20 percent in Phase 3.

CJC-1295 with DAC is a long-acting growth hormone releasing hormone analog that keeps growth hormone and IGF-1 elevated for about a week per injection. People use it for a steady rise in IGF-1 with only once or twice weekly dosing.

CJC-1295 without DAC, better known as Mod GRF 1-29, is a short-acting analog of growth hormone releasing hormone. People use it to prompt a natural-looking pulse of growth hormone, almost always paired with a GHRP like ipamorelin.

DSIP is a nine-amino-acid peptide first isolated from rabbit blood in 1977 and named for its apparent ability to promote delta-wave sleep. People use it for insomnia, stress, and pain, though the research picture is more mixed than the name suggests.

Epithalon is a four-amino-acid synthetic peptide from the Khavinson group designed to mimic epithalamin, a pineal gland extract. It is the best known longevity peptide, used for telomere support, sleep, and general anti-aging.

GHK-Cu is a naturally occurring tripeptide bound to copper that declines with age. It is used topically for skin firmness, wrinkles and hair growth, and by injection for wound healing, skin remodeling and general tissue repair.

GHRP-2 is a six amino acid ghrelin receptor agonist that produces a larger growth hormone pulse than ipamorelin but also raises cortisol and prolactin and stimulates appetite. It is licensed in Japan as a diagnostic test for growth hormone deficiency and is used off label in the community as a stronger, less selective alternative to ipamorelin.

GHRP-6 is the original growth hormone releasing peptide, a six amino acid ghrelin receptor agonist that produces a solid growth hormone pulse together with intense hunger and a rise in cortisol and prolactin. People use it when they want appetite as much as growth hormone, usually stacked with a GHRH analog.

Glutathione is a tripeptide of glutamate, cysteine and glycine that every cell makes as its main antioxidant. People use it by injection, IV, oral, liposomal or nebulized routes for oxidative stress, liver support, immune health and skin lightening.

Hexarelin is the most potent of the growth hormone releasing peptides on a per dose basis, with a larger pulse than GHRP-2 or GHRP-6. The trade offs are a rise in cortisol and prolactin and the fastest receptor desensitization in the class, which is why it is run in short cycles.

HGH is recombinant human growth hormone, a 191 amino acid protein identical to what the pituitary makes. It is an approved drug for growth hormone deficiency and is used off-label for fat loss, muscle preservation, recovery, and anti-aging.

IGF-1 LR3 is a modified, long-acting version of insulin-like growth factor 1 that resists binding proteins and stays active for most of a day. People use it for muscle growth and recovery, and it carries a real risk of low blood sugar.

Ipamorelin is a pentapeptide that triggers growth hormone release through the ghrelin receptor without the cortisol, prolactin, or hunger spikes seen with older GHRPs. It is the most popular GHRP in the community, usually stacked with a GHRH analog.

Kisspeptin-10 is the shortest active fragment of kisspeptin, the hypothalamic peptide that sits upstream of GnRH and acts as the master switch for the reproductive axis. People use it to boost LH and testosterone naturally, and research is exploring it for libido and fertility.

KPV is a three amino acid fragment of alpha-melanocyte stimulating hormone that carries the anti-inflammatory effect of the hormone without its pigmentation effect. It is used for inflammatory bowel symptoms, skin inflammation and general inflammation control.

LL-37 is the only human antimicrobial peptide of the cathelicidin family, a 37 amino acid fragment that white blood cells and skin cells release to kill microbes and break up biofilms. Research is almost entirely in test tubes and animals, with one small topical trial in leg ulcers. Injected LL-37 has essentially no human safety data.

Melanotan-1 is a stabilized analog of the natural tanning hormone alpha-MSH that darkens skin by stimulating melanin production. It is approved as an implant called Scenesse for a rare light sensitivity disorder and is used off-label for tanning and sun protection with fewer side effects than melanotan-2.

Melanotan-2 is a cyclic alpha-MSH analog that darkens skin quickly and also boosts libido and suppresses appetite because it hits several melanocortin receptors at once. It is the most widely used tanning peptide and the one with the most side effects.

MOTS-c is a 16-amino-acid peptide encoded in mitochondrial DNA that acts as a metabolic signal, improving insulin sensitivity and exercise capacity in mice. People use it for fat loss, endurance, and metabolic aging.

NAD+ is a coenzyme found in every living cell, not a peptide. It is central to energy metabolism and DNA repair, declines with age, and is injected or infused by people hoping to restore energy, cognition, and cellular resilience.

Oxytocin is a nine amino acid hormone from the pituitary that drives uterine contractions, milk letdown and a range of social behaviors. As an injection it is a hospital drug for childbirth. As a nasal spray it has been studied for autism, social anxiety and sexual function in small trials with mixed, mostly disappointing results.

PEG-MGF is a pegylated copy of the E domain peptide of mechano growth factor, the IGF-1 splice variant muscle produces after loading or damage. In rodents and cell cultures it activates satellite cells and promotes repair. There are no human trials of any kind, and the pegylated version sold online has barely been studied even in animals.

Pinealon is a three-amino-acid Khavinson bioregulator peptide (Glu-Asp-Arg) developed in St. Petersburg for brain aging and cognitive support. It is one of the shortest peptides sold and is taken orally or by injection.

PT-141 is a melanocortin receptor agonist that increases sexual desire and arousal by acting in the brain rather than on blood vessels. It is approved as Vyleesi for low sexual desire in premenopausal women and is widely used off-label by men and women for libido and erectile support.

Retatrutide is a once-weekly peptide that activates GLP-1, GIP and glucagon receptors together. Phase 2 data showed about 24 percent weight loss at 48 weeks, the largest figure reported for any single compound, but it is still years from approval.

Selank is a seven-amino-acid peptide derived from the immune peptide tuftsin, approved in Russia as a nasal anti-anxiety drug. People use it for calm focus without sedation.

Semaglutide is a once-weekly GLP-1 receptor agonist that cuts appetite and slows digestion, producing average weight loss around 15 percent in trials. It is the molecule behind the Ozempic and Wegovy brand names.

Semax is a seven-amino-acid peptide based on a fragment of ACTH, developed in Russia as a nasal drug for stroke recovery and cognitive impairment. People use it for focus, mental stamina, and mood support.

Sermorelin is the first 29 amino acids of natural growth hormone releasing hormone, the shortest fragment that still fully activates the receptor. It was once an approved diagnostic and pediatric drug and is now the most common growth hormone secretagogue prescribed by anti-aging and wellness clinics.

SLU-PP-332 is a small molecule, not a peptide, that activates the estrogen-related receptors to mimic the metabolic effects of endurance exercise. In mice it increased running endurance and reduced fat gain; no human data exist.

SNAP-8 is an eight amino acid cosmetic peptide that reduces the depth of expression wrinkles by interfering with the muscle contraction signal, in the same way as argireline but with a longer chain. It is used topically in serums and creams for forehead lines, crow's feet and frown lines.

SS-31 is a four-amino-acid peptide that concentrates in the inner mitochondrial membrane and binds cardiolipin, stabilizing energy production. As elamipretide it has been through multiple human trials, most notably for the rare mitochondrial disease Barth syndrome.

TB-500 is a synthetic version of the active region of thymosin beta-4, a protein found in nearly every human cell that regulates actin and cell movement. It is used for injury recovery, flexibility and general tissue repair, usually alongside BPC-157.

Tesamorelin is a stabilized growth hormone releasing hormone analog approved as Egrifta to reduce belly fat in people with HIV-related lipodystrophy. It is the GHRH analog with the strongest human evidence, and people use it off-label for visceral fat loss and general growth hormone support.

Thymosin alpha-1 is a 28 amino acid peptide originally isolated from the thymus that primes T cells and dendritic cells. It is a licensed drug in much of the world for chronic hepatitis B and immune support, and in the research market it is used for infections, immune weakness and general resilience.

Tirzepatide is a once-weekly peptide that activates both the GIP and GLP-1 receptors, producing average weight loss of about 20 percent at the top dose in trials. It is sold as Mounjaro for diabetes and Zepbound for weight management and sleep apnea.

VIP is a 28 amino acid neuropeptide found throughout the gut, lungs, brain and immune system that relaxes smooth muscle, widens blood vessels and calms inflammation. It is used, mostly as a nasal spray, for chronic inflammatory response syndrome from mold exposure, lung inflammation and immune regulation.